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Photodynamic Therapy (PDT)

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Photodynamic Therapy (PDT): A Light-Activated Treatment

Photodynamic Therapy instrument is a method of treating diseases based on the interaction of light, photosensitizer and oxygen. This method has been widely used in the field of dermatology in recent years, becoming a new noninvasive method for the treatment of various benign malignancies, infectious diseases, acne and other diseases. 

It is a minimally invasive cancer treatment that uses light-activated drugs to selectively destroy malignant cells in early-stage or superficial tumors of the skin, esophagus, lungs, and other accessible areas while preserving healthy tissue.

How It Works

Photodynamic Therapy (PDT) involves three key components: a photosensitizing agent, light of a specific wavelength, and oxygen. The process begins with the administration of the photosensitizer, which accumulates selectively in abnormal tissues, such as cancer cells. When the targeted area is exposed to light of the appropriate wavelength, the photosensitizer becomes activated. This interaction generates reactive oxygen species (ROS), such as singlet oxygen, which induce cell death by damaging cellular structures and disrupting vital functions in the targeted cells.

Conditions Treated:

PDT has a wide range of applications in medical practice, including:

  • Cancer Treatment: Effective for skin cancers, esophageal cancer, lung cancer, and head and neck cancers.
  • Dermatology: Used to treat precancerous skin conditions like actinic keratosis and non-cancerous skin lesions such as acne and psoriasis.
  • Ophthalmology: Treats certain conditions like age-related macular degeneration (AMD).
  • Infections: Emerging uses for antimicrobial applications, including targeting drug-resistant bacteria and fungi.

Advantages of Photodynamic Therapy

  • Minimally Invasive: Causes less pain and trauma compared to surgery.
  • Selective Targeting: Photosensitizers can focus on abnormal tissues, minimizing damage to surrounding healthy cells.
  • Repeatable: Can be used multiple times on the same site if necessary.
  • Short Recovery Time: Patients typically experience a quicker recovery compared to traditional treatments.

Key Benefits of Photodynamic Therapy

  • Minimally Invasive – No cutting, minimal scarring
  • Precision Treatment – Targets only affected areas
  • Versatile Applications – Used for skin cancer, acne, HPV, and anti-aging
  • Fast Recovery – Little to no downtime