{"id":1700,"date":"2026-04-01T08:27:42","date_gmt":"2026-04-01T08:27:42","guid":{"rendered":"https:\/\/slcelitemedicalcare.com\/?page_id=1700"},"modified":"2026-04-01T14:33:30","modified_gmt":"2026-04-01T14:33:30","slug":"next-generation-sequencing-ngs","status":"publish","type":"page","link":"https:\/\/slcelitemedicalcare.com\/id\/next-generation-sequencing-ngs\/","title":{"rendered":"Pengurutan Generasi Berikutnya (NGS)"},"content":{"rendered":"
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Pengurutan Generasi Berikutnya (NGS)<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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  • \n\t\t\t\t\t\t\t\t\t\tRumah<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t
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    Next-Generation Sequencing (NGS): A Simple Guide to Decoding Your Cancer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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    What Is Next-Generation Sequencing (NGS)?<\/strong><\/p>

    Pengurutan Generasi Berikutnya (NGS)<\/strong> is a powerful technology that reads the genetic blueprint of your cancer\u2014identifying the specific mutations, markers, and vulnerabilities that make your tumor unique.<\/p>

    Think of it as a high-tech detective<\/strong> that looks at hundreds of clues at once to create a complete picture of your cancer.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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    How Is NGS Different from Traditional Testing?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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    Traditional Testing<\/b><\/p><\/th>

    NGS<\/b><\/p><\/th><\/tr><\/thead>

    Tests 1\u20135 genes at a time<\/span><\/p><\/td>

    Tests\u00a0<\/span>hundreds of genes<\/b>\u00a0at once<\/span><\/p><\/td><\/tr>

    May miss rare mutations<\/span><\/p><\/td>

    Captures\u00a0<\/span>all<\/b>\u00a0mutations<\/span><\/p><\/td><\/tr>

    Multiple biopsies may be needed<\/span><\/p><\/td>

    One sample gives complete picture<\/span><\/p><\/td><\/tr>

    Slower results<\/span><\/p><\/td>

    Faster turnaround<\/span><\/p><\/td><\/tr><\/tbody><\/table>

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    How NGS Works: A Simple Analogy\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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    Imagine your cancer is a book with many chapters. Traditional testing reads one page at a time. NGS reads the entire book at once<\/strong>\u2014finding every typo, missing page, or hidden message that matters.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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    The NGS Process in 4 Steps<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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    Melangkah<\/b><\/p><\/th>

    Apa yang Terjadi<\/b><\/p><\/th><\/tr><\/thead>

    1. Sample Collection<\/span><\/p><\/td>

    A small piece of tumor (biopsy) or a simple blood draw (liquid biopsy) is taken<\/span><\/p><\/td><\/tr>

    2. DNA Extraction<\/span><\/p><\/td>

    The genetic material is extracted from your cancer cells<\/span><\/p><\/td><\/tr>

    3. Sequencing<\/span><\/p><\/td>

    Advanced machines read hundreds of genes simultaneously<\/span><\/p><\/td><\/tr>

    4. Analysis<\/span><\/p><\/td>

    Specialists interpret the results to find actionable mutations<\/span><\/p><\/td><\/tr><\/tbody><\/table>

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    What NGS Reveals About Your Cancer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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    NGS identifies:<\/strong><\/p>

    \u2705 Driver Mutations<\/strong> \u2013 The genetic changes that cause cancer to grow
    \u2705 Targetable Mutations<\/strong> \u2013 Genes that can be treated with precision drugs
    \u2705 Resistance Mutations<\/strong> \u2013 Why cancer stopped responding to treatment
    \u2705 Tumor Mutational Burden (TMB)<\/strong> \u2013 How many mutations your cancer has (helps predict immunotherapy response)
    \u2705 MSI Status<\/strong> \u2013 Whether your cancer may respond to certain immunotherapies
    \u2705 Hereditary<\/strong> Mutations<\/strong> \u2013 Genetic changes you inherited that increase cancer risk<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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    Liquid Biopsy: A Non-Invasive Option<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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    NGS can be performed on a simple blood draw<\/strong> (liquid biopsy), which:<\/p>

    \u2705 Avoids invasive tissue biopsy
    \u2705 Captures tumor DNA circulating in the blood
    \u2705 Monitors treatment response in real-time
    \u2705 Detects emerging resistance early
    \u2705 Ideal for patients who cannot undergo tissue biopsy<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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    What Cancers Can Benefit from NGS?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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    Jenis Kanker<\/span><\/p><\/th>

    What NGS Reveals<\/span><\/p><\/th><\/tr><\/thead>

    Kanker Paru-paru<\/b><\/p><\/td>

    EGFR, ALK, ROS1, RET, MET, KRAS, NTRK, TMB<\/span><\/p><\/td><\/tr>

    Kanker payudara<\/b><\/p><\/td>

    HER2, BRCA1\/2, PIK3CA, ESR1, MSI<\/span><\/p><\/td><\/tr>

    Colorectal Cancer<\/b><\/p><\/td>

    RAS, BRAF, MSI, NTRK, HER2<\/span><\/p><\/td><\/tr>

    Prostate Cancer<\/b><\/p><\/td>

    BRCA1\/2, ATM, MSI, AR mutations<\/span><\/p><\/td><\/tr>

    Ovarian Cancer<\/b><\/p><\/td>

    BRCA1\/2, MSI, HRD<\/span><\/p><\/td><\/tr>

    Melanoma<\/b><\/p><\/td>

    BRAF, NRAS, c-KIT, TMB<\/span><\/p><\/td><\/tr>

    Blood Cancers<\/b><\/p><\/td>

    FLT3, IDH1\/2, KMT2A, and many others<\/span><\/p><\/td><\/tr>

    Kanker pankreas<\/b><\/p><\/td>

    KRAS, BRCA, MSI, NTRK<\/span><\/p><\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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    Benefits of NGS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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    \u2705 Comprehensive<\/strong> \u2013 Hundreds of genes tested at once
    \u2705 Fast<\/strong> \u2013 Results in days to weeks
    \u2705 Actionable<\/strong> \u2013 Guides targeted therapy, immunotherapy, and clinical trial options
    \u2705 Non-Invasive Option<\/strong> \u2013 Liquid biopsy available
    \u2705 Cost-Effective<\/strong> \u2013 Avoids ineffective treatments
    \u2705 Personalized<\/strong> \u2013 Treatment designed around YOUR cancer’s unique genetics<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

    Home Next-Generation Sequencing (NGS) Next-Generation Sequencing (NGS): A Simple Guide to Decoding Your Cancer What Is Next-Generation Sequencing (NGS)? Next-Generation Sequencing (NGS) is a powerful technology that reads the genetic blueprint of your cancer\u2014identifying the specific mutations, markers, and vulnerabilities that make your tumor unique. Think of it as a high-tech detective that looks at […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-1700","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/slcelitemedicalcare.com\/id\/wp-json\/wp\/v2\/pages\/1700","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/slcelitemedicalcare.com\/id\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/slcelitemedicalcare.com\/id\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/slcelitemedicalcare.com\/id\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/slcelitemedicalcare.com\/id\/wp-json\/wp\/v2\/comments?post=1700"}],"version-history":[{"count":0,"href":"https:\/\/slcelitemedicalcare.com\/id\/wp-json\/wp\/v2\/pages\/1700\/revisions"}],"wp:attachment":[{"href":"https:\/\/slcelitemedicalcare.com\/id\/wp-json\/wp\/v2\/media?parent=1700"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}